The researchers put 20 healthy men in an air pressure chamber. Within 10 minutes, they reduced the air pressure to 76 kilopascals, which is about the equivalent of an aircraft cabin. After two hours, the researchers examined the subjects' blood for important blood coagulation factors. By 2.5 times, the levels of prothrombin factors 1 and 2 had increased. The thrombin-antithrombin complexes had also increased 8.2-fold. From this, the authors conclude that the rapid switch to low air pressure, such as when flying, increases the risk of venous thrombosis.
The authors contradict the results of their study by Kraaijenhagen and colleagues. The researchers argued that there is no increased risk of venous thrombosis on long trips. (Read the report of October 27, 2000. (Source: Deutsches Ärzteblatt)Dagmar Kronenberg